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Ortiz Z, et al. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (review). The Cochrane Collaboration. Published by JohnWiley & Sons, Ltd. 2009.

Folaţii sunt compuşi ai acidului pteroilglutamic, care funcţioneazacid folic bioclinicaă ca şi coenzime în reacţii metabolice care implică transferul unei unităţi de carbon. Folaţii şi vitamina B12 sunt esenţiali。

Diagnosticul de laborator al deficitului de acid folic include măsurarea acidului folic seric și a celui eritrocitar. În sânge, 95 % din acidul folic este în eritrocite. Prin urmare acidul folic eritrocitar。

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